Familial Hypercholesterolaemia (adult)
The UK NSC policy on Familial Hypercholesterolaemia screening in adults
Familial hypercholesterolaemia (or hyperlipidaemias) are inherited metabolic disorders which include harmful disorders resulting in an excess of cholesterol and/or triglyceride in the blood. Cholesterol is transported round the body in combination with proteins, known as lipoproteins, low density lipoproteins (LDL) and beneficial high density lipoproteins (HDL). Triglyceride travels within very low density lipoproteins (VLDL) and chylomicrons.
A national screening programme for FH is not recommended.
This policy was reviewed in Dec 2011 but no significant changes were made. It is due to be considered again in 2014/15, or earlier if significant new evidence emerges.
Evidence Supporting the Policy
See expert review.
British Heart Foundation
British Inherited Metabolic Disease Group
Genetic Alliance UK
Royal College of Pathologists
Royal College of Physicians
Royal College of Physicians and Surgeons of Glasgow
Royal College of Physicians of Edinburgh
Scottish Lipid Forum
The stakeholder groups will be involved when the policy is next reviewed. If you think your organisation should be added, please contact us.